Wireless mobile ad-hoc sensor networks for very large scale cattle monitoring

This paper investigates the use of wireless mobile ad hoc sensor networks in the nationwide cattle monitoring systems. This problem is essential for monitoring general animal health and detecting outbreaks of animal diseases that can be a serious threat for the national cattle industry and human health. We begin by describing a number of related approaches for supporting animal monitoring applications and identify a comprehensive set of requirements that guides our approach. We then propose a novel infrastructure-less, self -organized peer to peer architecture that fulfills these requirements. The core of our work is the novel data storage and routing protocol for large scale, highly mobile ad hoc sensor networks that is based on the Distributed Hash Table (DHT) substrate that we optimize for disconnections. We show over a range of extensive simulations that by exploiting nodes’ mobility, packet overhearing and proactive caching we significantly improve availability of sensor data in these extreme conditions

Wireless mobile ad-hoc sensor networks for very large scale cattle monitoring

This paper investigates the use of wireless mobile ad hoc sensor networks in the nationwide cattle monitoring systems. This problem is essential for monitoring general animal health and detecting outbreaks of animal diseases that can be a serious threat for the national cattle industry and human health. We begin by describing a number of related approaches for supporting animal monitoring applications and identify a comprehensive set of requirements that guides our approach. We then propose a novel infrastructure-less, self -organized peer to peer architecture that fulfills these requirements. The core of our work is the novel data storage and routing protocol for large scale, highly mobile ad hoc sensor networks that is based on the Distributed Hash Table (DHT) substrate that we optimize for disconnections. We show over a range of extensive simulations that by exploiting nodes’ mobility, packet overhearing and proactive caching we significantly improve availability of sensor data in these extreme conditions

Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments

Pervasive gaming is a new form of multimedia entertainment that extends the traditional computer gaming experience out into the real world. Through a combination of personal devices, positioning systems and other sensors, combined with wireless networking, a pervasive game can respond to player's movements and context and enable them to communicate with a game engine and other players. We review our recent deployment examples of pervasive games in order to explain their distinctive characteristics as wireless ad-hoc networking applications. We then identify the network support challenges of scaling pervasive games to include potentially mass numbers of players across extremely heterogeneous and unreliable networks. We propose a P2P overlay capable of storing large amount of game related data, which is the key to combating the loss of coverage and potential dishonesty of players. The proposed protocol decreases the deployment costs of the gaming infrastructure by self organization and utilizing storage space of users' devices. We demonstrate scalability and increased availability of data offered by the proposed protocol in simulation based evaluatio

Increasing communication reliability in manufacturing environments

This paper is concerned with low cost mechanisms that can increase reliability of machine to machine and machine to cloud communications in increasingly complex manufacturing environments that are prone to disconnections and faults. We propose a novel distributed and cooperative sensing framework that supports localized real time predictive analytics of connectivity patterns and detection of a range of faults together with issuing of notifications and responding on demand queries. We show that our Fault and Disconnection Aware Smart Sensing (FDASS) framework achieves significantly lower packet loss rates and communication delays in the face of unreliable nodes and networks when compared to the state of the art and benchmark approaches

Practical mobile ad hoc networks for large scale cattle monitoring

This thesis is concerned with identification of realistic requirements for the cattle monitoring system and design of the practical architecture addressing these requirements. Automated monitoring of cattle with wireless monitoring devices mounted on the animals can increase efficiency of cattle production, decrease its reliance on human labour and thus increase its profitability. Multi-hop ad hoc wireless communication has the potential to increase battery life of the animal mounted devices, decrease their size and combat disconnections. This thesis reveals that no current approach sufficiently addresses energy constrains of the animal mounted devices and potential disconnections. We propose a delay tolerant store and forward architecture that provides data retention, detecting custom events, issues notifications, answers remote and in-situ queries, based on requirements identified during field experiments we conducted. This architecture utilizes fixed infrastructure but also works in ad hoc infrastructureless conditions. The core of the proposed architecture, Mobile Ad Hoc Network (MANET) communication, provides offloading data for long term storage by sending data to farm servers via sinks that are a part of MANET and handles in-situ queries issued by users collocated with the animals. The proposed MANET routing algorithm addresses high mobility of nodes and disconnections. It provides lower and more balanced energy usage, shorter delays and increased success ratio of delivering answers to in-situ queries than more generic existing approaches. Problems of large scale deployment of the envisaged system are also addressed. We discuss the necessary configuration process performed during the system installation as well as pervasive mobile and home access to the target system. We propose cost efficient strategies for sinks installation and connecting sinks to farm servers, adaptive to different requirements, estates layout, available infrastructure and existing human and vehicle mobility. We also propose a cost efficient security model for the target system based on public key cryptography

Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues

Histone deacetylase (HDAC) inhibitors are a class of drugs used in the cancer treatment. Here, we developed a library of 19 analogues of Vorinostat, an HDAC inhibitor used in lymphomas treatment. In Vorinostat, we replaced the hydrophobic phenyl group with various tricyclic ‘caps’ possessing a central, eight-membered, heterocyclic ring, and investigated the HDAC activity and cytotoxic effect on the cancer and normal cell lines. We found that 3 out of the 19 compounds, based on dibenzo[b,f]azocin-6(5H)-one, 11,12-dihydrodibenzo[b,f]azocin- 6(5H)-one, and benzo[b]naphtho[2,3-f][1,5]diazocine-6,14(5H,13H)-dione scaffolds, showed better HDACs inhibition than the referenced Vorinostat. In leukemic cell line MV4-11 and in the lymphoma cell line Daudi, three compounds showed lower IC50 values than Vorinostat. These compounds had higher activity and selectivity against MV4-11 and Daudi cell lines than reference Vorinostat. We also observed a strong correlation between HDACs inhibition and the cytotoxic effect. Cell lines derived from solid tumours: A549 (lung carcinoma) and MCF-7 (breast adenocarcinoma) as well as reference BALB/3T3 (normal murine fibroblasts) were less susceptible to compounds tested. Developed derivatives show improved properties than Vorinostat, thus they could be considered as possible agents for leukemia and lymphoma treatment

Practical mobile ad hoc networks for large scale cattle monitoring

This thesis is concerned with identification of realistic requirements for the cattle monitoring system and design of the practical architecture addressing these requirements. Automated monitoring of cattle with wireless monitoring devices mounted on the animals can increase efficiency of cattle production, decrease its reliance on human labour and thus increase its profitability. Multi-hop ad hoc wireless communication has the potential to increase battery life of the animal mounted devices, decrease their size and combat disconnections. This thesis reveals that no current approach sufficiently addresses energy constrains of the animal mounted devices and potential disconnections. We propose a delay tolerant store and forward architecture that provides data retention, detecting custom events, issues notifications, answers remote and in-situ queries, based on requirements identified during field experiments we conducted. This architecture utilizes fixed infrastructure but also works in ad hoc infrastructureless conditions. The core of the proposed architecture, Mobile Ad Hoc Network (MANET) communication, provides offloading data for long term storage by sending data to farm servers via sinks that are a part of MANET and handles in-situ queries issued by users collocated with the animals. The proposed MANET routing algorithm addresses high mobility of nodes and disconnections. It provides lower and more balanced energy usage, shorter delays and increased success ratio of delivering answers to in-situ queries than more generic existing approaches. Problems of large scale deployment of the envisaged system are also addressed. We discuss the necessary configuration process performed during the system installation as well as pervasive mobile and home access to the target system. We propose cost efficient strategies for sinks installation and connecting sinks to farm servers, adaptive to different requirements, estates layout, available infrastructure and existing human and vehicle mobility. We also propose a cost efficient security model for the target system based on public key cryptography.EThOS - Electronic Theses Online ServiceGBUnited Kingdo